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ELUAN, K., SALAMA, U., IBRAHIM, A., ABDEL-FATAH, T., DAOUD, A. (2005). CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE. Egyptian Journal of Agricultural Research, 83(3), 1425-1432. doi: 10.21608/ejar.2005.247858
KHAIRAT A. ELUAN; ULLY S. SALAMA; ALFONS M. IBRAHIM; TARADI ABDEL-FATAH; AHMED M. DAOUD. "CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE". Egyptian Journal of Agricultural Research, 83, 3, 2005, 1425-1432. doi: 10.21608/ejar.2005.247858
ELUAN, K., SALAMA, U., IBRAHIM, A., ABDEL-FATAH, T., DAOUD, A. (2005). 'CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE', Egyptian Journal of Agricultural Research, 83(3), pp. 1425-1432. doi: 10.21608/ejar.2005.247858
ELUAN, K., SALAMA, U., IBRAHIM, A., ABDEL-FATAH, T., DAOUD, A. CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE. Egyptian Journal of Agricultural Research, 2005; 83(3): 1425-1432. doi: 10.21608/ejar.2005.247858

CALCIUM PHOSPHATE AS AN ADJUVANT FOR INACTIVATED RIFT VALLEY FEVER VACCINE

Article 28, Volume 83, Issue 3, September 2005, Page 1425-1432  XML PDF (203.05 K)
Document Type: Original Article
DOI: 10.21608/ejar.2005.247858
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Authors
KHAIRAT A. ELUAN; ULLY S. SALAMA; ALFONS M. IBRAHIM; TARADI ABDEL-FATAH; AHMED M. DAOUD
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt
Abstract
Vaccination to protect animal against infectious diseases may be enhanced by using adjuvant that can selectively stimulate immunoregulatory responses. A novel adjuvant composed of calcium phosphate (CAP) was compared with the commonly used aluminum hydroxide gel adjuvant for its ability to induce immunity to Rift Valley Fever virus. Results indicated that CAP was more potent as an adjuvant than alum, induced high titers of antibody. Furthermore, it is economical, simple to manufacture and it is a natural constituent of the animal body. 
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