IMPROVEMENT OF INACTIVATED AVIAN REO VIRUS VACCINE BY USING BINARY ETHYLENEIMINE

ABOU EL-KHAIR, MOHAMED A.; ABDEL-BAKY, MANSOUR H.

doi:10.21608/ejar.2004.274850

IMPROVEMENT OF INACTIVATED AVIAN REO VIRUS VACCINE BY USING BINARY ETHYLENEIMINE

Document Type : Original Article

Authors

¹ Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt

² Central Lab for Evaluation of Veterinary Biologics, Agricultural Research Center Ministry of Agriculture, Dokki, Giza, Egypt

10.21608/ejar.2004.274850

Abstract

A comparative study was done between the immunogenic response induced in two groups of one week old chicks vaccinated with formalin-inactivated and binary ethyleneimine (BB) vaccines of avian Reo virus. Chickens were bled weekly for 8 weeks post-vaccination and tested for neutralizing antibodies. Vaccinated and non-vaccinated control groups of chicks were challenged with virulent virus at the 3"¹ week post-vaccination. Chicks immunized with binary ethyleneimine inactivated vaccine had a higher level of serum neutralizing antibodies. However, both vaccinated groups were protected when challenged.