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EL-MAKAKY, H., ABOUL EL-KHAIR, M., EL-KOFFY, M., MADKOUR, M., IBRAHIM, N., AL. BORDINY, F. (2004). TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE. Egyptian Journal of Agricultural Research, 82(3), 1439-1453. doi: 10.21608/ejar.2004.274856
HALA M. EL-MAKAKY; MOHAMED A. ABOUL EL-KHAIR; MERVAT A. EL-KOFFY; MOHAMED S. MADKOUR; NADIA M. IBRAHIM; FEKRIA AL. BORDINY. "TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE". Egyptian Journal of Agricultural Research, 82, 3, 2004, 1439-1453. doi: 10.21608/ejar.2004.274856
EL-MAKAKY, H., ABOUL EL-KHAIR, M., EL-KOFFY, M., MADKOUR, M., IBRAHIM, N., AL. BORDINY, F. (2004). 'TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE', Egyptian Journal of Agricultural Research, 82(3), pp. 1439-1453. doi: 10.21608/ejar.2004.274856
EL-MAKAKY, H., ABOUL EL-KHAIR, M., EL-KOFFY, M., MADKOUR, M., IBRAHIM, N., AL. BORDINY, F. TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE. Egyptian Journal of Agricultural Research, 2004; 82(3): 1439-1453. doi: 10.21608/ejar.2004.274856

TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE

Article 30, Volume 82, Issue 3, September 2004, Page 1439-1453  XML PDF (3.28 MB)
Document Type: Original Article
DOI: 10.21608/ejar.2004.274856
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Authors
HALA M. EL-MAKAKY; MOHAMED A. ABOUL EL-KHAIR; MERVAT A. EL-KOFFY; MOHAMED S. MADKOUR; NADIA M. IBRAHIM; FEKRIA AL. BORDINY
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt
Abstract
Inactivated monovalent and bivalent oil adjuvanted vaccines against Avian Encephalomyelitis (AE) and Reo viruses were prepared. Immunological responses to such experimental vaccines were evaluated by injecting them into groups of susceptible thickens. Blood samples were collected at weekly intervals. Serological and cellular immune response were evaluated by SNT, lymphocyte blastogenesis and macrophage activity test, respectively. The vaccinated chicks were subjected to challenge tests against both viruses. The results indicated that prepared vaccine was effident, safe, immunogenic and produced satisfactory dual protection against AE and Reo viruses infection.
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