TALAAT, A., ALI, M., SALAMA, L. (2004). IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE. Egyptian Journal of Agricultural Research, 82(4), 1893-1904. doi: 10.21608/ejar.2004.275798
ABEER A. TALAAT; MERVATE M. ALI; LILY S. SALAMA. "IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE". Egyptian Journal of Agricultural Research, 82, 4, 2004, 1893-1904. doi: 10.21608/ejar.2004.275798
TALAAT, A., ALI, M., SALAMA, L. (2004). 'IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE', Egyptian Journal of Agricultural Research, 82(4), pp. 1893-1904. doi: 10.21608/ejar.2004.275798
TALAAT, A., ALI, M., SALAMA, L. IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE. Egyptian Journal of Agricultural Research, 2004; 82(4): 1893-1904. doi: 10.21608/ejar.2004.275798
IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt
Abstract
A combined vaccine was constructed to contain FMD 01, RVF ZH5,01 and sheep pox Egyptian strain inactivated with Binary ethylenemine (BEI) and adsorbed on aluminium hydroxide gel. Comparative studies were conducted to evaluate the prepared vaccines (three monovalent FMD, RVF and Sheep Pox separately and the combined one). It was found that the serum neutralization antibody titer of sheep vaccinated with the combined vaccine (FMD and RVF) reached its peak earlier than those vaccinated with each as monovalent vaccine, separately, while, there was no significant difference in efficacy of immune response between combined vaccine and sheep pox vaccine. So, it is recommended that animals should be boostered at the 4th week post the first dose.
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