Home Articles List Article Information
Egyptian Journal of Agricultural Research
Journal Archive
Volume Volume 102 (2024)
Volume Volume 101 (2023)
Volume Volume 100 (2022)
Volume Volume 99 (2021)
Volume Volume 98 (2020)
Volume Volume 97 (2019)
Volume Volume 96 (2018)
Volume Volume 95 (2017)
Volume Volume 94 (2016)
Volume Volume 93 (2015)
Volume Volume 92 (2014)
Volume Volume 91 (2013)
Volume Volume 90 (2012)
Volume Volume 89 (2011)
Volume Volume 88 (2010)
Volume Volume 87 (2009)
Volume Volume 86 (2008)
Volume Volume 85 (2007)
Volume Volume 84 (2006)
Volume Volume 83 (2005)
Volume Volume 82 (2004)
Volume Volume 81 (2003)
Volume Volume 80 (2002)
Volume Volume 79 (2001)
Volume Volume 78 (2000)
Volume Volume 77 (1999)
Volume Volume 76 (1998)
DAOUD, A., MAHMOUD, M., FADL, H., YOUSSEF, E., HASSAN, H. (2003). PRODUCTION AND EVALUATION OF A NEWLY ADJUVANTED RABBIT PASTEURELLOSIS VACCINE. Egyptian Journal of Agricultural Research, 81(4), 1905-1917. doi: 10.21608/ejar.2003.298972
AHMED M. DAOUD; MANAL S. MAHMOUD; HALA A. FADL; ELHAM A. YOUSSEF; HASSAN A. HASSAN. "PRODUCTION AND EVALUATION OF A NEWLY ADJUVANTED RABBIT PASTEURELLOSIS VACCINE". Egyptian Journal of Agricultural Research, 81, 4, 2003, 1905-1917. doi: 10.21608/ejar.2003.298972
DAOUD, A., MAHMOUD, M., FADL, H., YOUSSEF, E., HASSAN, H. (2003). 'PRODUCTION AND EVALUATION OF A NEWLY ADJUVANTED RABBIT PASTEURELLOSIS VACCINE', Egyptian Journal of Agricultural Research, 81(4), pp. 1905-1917. doi: 10.21608/ejar.2003.298972
DAOUD, A., MAHMOUD, M., FADL, H., YOUSSEF, E., HASSAN, H. PRODUCTION AND EVALUATION OF A NEWLY ADJUVANTED RABBIT PASTEURELLOSIS VACCINE. Egyptian Journal of Agricultural Research, 2003; 81(4): 1905-1917. doi: 10.21608/ejar.2003.298972

PRODUCTION AND EVALUATION OF A NEWLY ADJUVANTED RABBIT PASTEURELLOSIS VACCINE

Article 28, Volume 81, Issue 4, December 2003, Page 1905-1917  XML PDF (3.17 MB)
Document Type: Original Article
DOI: 10.21608/ejar.2003.298972
View on SCiNiTO View on SCiNiTO
Authors
AHMED M. DAOUD; MANAL S. MAHMOUD; HALA A. FADL; ELHAM A. YOUSSEF; HASSAN A. HASSAN
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt
Abstract
Rabbit pasteurellosis aluminium hydroxide gel adjuvanted vaccine (ALV) and aqueous formalized one (AV) were evaluated serologically and by 2-stage protection bioassay. Evaluation in mice revealed a good pro­tection level (85%) in either ALV or AV vaccinates, when subjected to homogenous challenge exposure. In rabbits, both vaccines stimulated satisfactory and significantly differed antibody levels. However, level re­corded in ALV vaccinates persisted for more prolonged period (16th week post-boostering, PB) than in case of AV. Moreover, sera from rab­bits immunized with ALV or AV form passively protected mice at a levels of 70% and 60%, respectively. The let-stage bioassay conducted at ri weeks PB revealed no difference in the level of protective immunity (80%) between rabbits vaccinated with either forms of vaccines. However, the 2m-stage bioas­say conducted at 16th week PB revealed a superior protective level (70%) in ALV vaccinates versus 50% only in AV ones. The ALV-based Pasteur°Ua vaccine proved to be safe and effec­tive alternative to the classical aqueous one for controlling P. multocida infection in rabbits.
Statistics
Article View: 43
PDF Download: 195