HUSIEN, M., YOUNIS, A. (2000). EFFICACY AND RESIDUES OF OXOLINIC ACID IN OREOCHROMIS NILOTICUS FISH INFECTED WITH ENTERIC RED MOUYH DISEASE (ERM). Egyptian Journal of Agricultural Research, 78(1), 399-409. doi: 10.21608/ejar.2000.321705
MONA M. HUSIEN; ABAS A. YOUNIS. "EFFICACY AND RESIDUES OF OXOLINIC ACID IN OREOCHROMIS NILOTICUS FISH INFECTED WITH ENTERIC RED MOUYH DISEASE (ERM)". Egyptian Journal of Agricultural Research, 78, 1, 2000, 399-409. doi: 10.21608/ejar.2000.321705
HUSIEN, M., YOUNIS, A. (2000). 'EFFICACY AND RESIDUES OF OXOLINIC ACID IN OREOCHROMIS NILOTICUS FISH INFECTED WITH ENTERIC RED MOUYH DISEASE (ERM)', Egyptian Journal of Agricultural Research, 78(1), pp. 399-409. doi: 10.21608/ejar.2000.321705
HUSIEN, M., YOUNIS, A. EFFICACY AND RESIDUES OF OXOLINIC ACID IN OREOCHROMIS NILOTICUS FISH INFECTED WITH ENTERIC RED MOUYH DISEASE (ERM). Egyptian Journal of Agricultural Research, 2000; 78(1): 399-409. doi: 10.21608/ejar.2000.321705
EFFICACY AND RESIDUES OF OXOLINIC ACID IN OREOCHROMIS NILOTICUS FISH INFECTED WITH ENTERIC RED MOUYH DISEASE (ERM)
Animal Health Research Institute, Agricultural Research Centre, Dokki, Giza, Egypt
Abstract
Efficacy and residues of oxolinic acid in tissues of experimentally inoculated Oreochromis niloticus fish with Yersinia ruckeri (Y.rucken) have been investigated. Results of the in-vitro stuy revealed that the used bacterial isolate was sensitive to oxolinic acid. The in-vivo treatment test indicated a high effectiveness of oxolinic acid when given orally in the diet at a dose rate of 10 mg/kg body weight for ten successive days. The haematological inestigations in experimentally infected fish proved a decrease in some blood parameters namely, RBCs, WBCs count, Hb content and P.C.V. volume pre-treatment with oxolinic acid, but they returned to their normal values post-treatment. The residual analysis indicated the presence of oxolinic acid residues in the muscles, kidney and liver of treated fish up to 15, 20 and 25 days post-treatment, resppectively.
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