OSFOR, M., ABDEL-WAHAB, A., METAWA, H., ARBID, M., TAWFIK, A. (2001). STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS. Egyptian Journal of Agricultural Research, 79(1), 309-318. doi: 10.21608/ejar.2001.397679
MOSTAFA M. H. OSFOR; AMR M. ABDEL-WAHAB; HISHAM METAWA; MAHMOUD S. S. ARBID; AHMED TAWFIK. "STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS". Egyptian Journal of Agricultural Research, 79, 1, 2001, 309-318. doi: 10.21608/ejar.2001.397679
OSFOR, M., ABDEL-WAHAB, A., METAWA, H., ARBID, M., TAWFIK, A. (2001). 'STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS', Egyptian Journal of Agricultural Research, 79(1), pp. 309-318. doi: 10.21608/ejar.2001.397679
OSFOR, M., ABDEL-WAHAB, A., METAWA, H., ARBID, M., TAWFIK, A. STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS. Egyptian Journal of Agricultural Research, 2001; 79(1): 309-318. doi: 10.21608/ejar.2001.397679
STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS
2Faculty of Agriculture, El-Minia University, Egypt
3Animal Health Research institute, Agricultural Research Centre, Dokki, Giza, Egypt
Abstract
This study was conducted on 50 male subjects with an age ranging 31 to 54 years with mean of 43.6 ± 8.1, divided into two groups: group one included 30 male subjects with the diagnosis of chronic hepatitis C, and group two included 20 age matched normal volunteers. Both groups were subjected to clinical examination, liver functions, abdominal sonography, polyrnorase chain reaction (PCR) for Hepatitis C virus (FICV), determination o/ serum iron, zinc. copper, and magnesium, lipoprotein profile. In addition patients, group were subjected to liver biopsy and estimation of histology activity index. Results showed no significant difference between patients mean serum iron (129.2 ± 41 ug/ dl) and control (101.45 ± 33.5 ug/c11) 'P < 0,269'; between patients mean serum copper (105.4 = 27_6 ug/dI) and control (104.95 ± 24.29 ugf dl) P < 0.359", between patients mean serum zinc level (140.6 ± 12.6 ug(dl) and control (137.63 ± 14.06 ug/dI) P < 0.347", between patients mean serum magnesium (20.817 ± 2.924 ug/dI) and control (21.66 ± 2.33 ugid1): P = 0,24". Lipoprotein profile showed no significant difference between serum cholesterol. triglycerides, LDL, HDL in both groups_ We found elevated serum iron in 6 patients (20%), elevated serum copper in 5 patients (16.7%) and elevated serum magnesium in two patients (6.7%) in diseased group. Only HDL showed significant positive correlation with histological activity index (Pe 0.01)_ in conclusion, there is no correlation between studied serum trace elements and severity of chronic hepatitis.
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