EVALUATION OF INACTIVATED BVD VACCINE IN SHEEP

Document Type : Original Article

Author

Veterinary Serum and Vaccine Research Institute, Agricultural Research Centre, Ministry of Agriculture, Dokki, Giza, Egypt

Abstract

To study the efficacy of inactivated BVD virus for protection of the Baladi sheep against pestivirus infection (Border disease), BVD­antibody free twelve Iambs were immunized with two doses of the locally prepared BVD, IBR and P1-3 combined inactivated vaccine (Pneu­mo-3 vaccine) 2 weeks apart. Challenge test was done one month after the first inoculation. The vaccine evoked resistance against the chal­lenge with virulent BVD virus, and a protective level of antibodies per­sisted up to the 6th month after vaccination.