Document Type : Original Article
                            
                        
                                                    Authors
                            
                                                            
                                                                        Central Laboratory for control of Veterinary Biologics, Agricultural Research Centre, Egypt                                
                            
                                                                            
                        
                        
                            Abstract
                            Eight-hundred and thirty three (833) samples of biological products ("31 5" live attenuated egg adapted vaccines, "1 93" live attenuated tissue culture adapted vaccines, "268" inactivated vaccines, "12" antigens, "9" anti-tetanic serum, 11 normal serum (neoborn calf serum, fetal calf serum, horse and swine serum and "25" physiological saline) were screened against common contaminants (Bacterial, Fungal and Mycoplasmal), and antibiotic sensitivity to these contaminants were determined. The results revealed that, out of the total number of samples (833), 18 samples (2.2%) were contaminated with various types of contaminants (anthracoid "6", proteus "5", fungus "2", staphylococci 2, E.coli1, Mycoplasma 1 and streptococci 1). Concerning the results of antibiotic sensitivity test, it was clear that anthracoid, proteus, fungi, E.coli and Mycoplasma were sensitive to chloramphenicol, P-nitrophenyl glycerol, mycostatine, amoxycillin, and lincospectin, respectively, with varying degrees. Staphylococci and streptococci contaminants were sensitive to benzyl penicillin. By application of this study, it is possible to control the contaminants which interfere the production of different veterinary biologics.